Only three places in the Bible mention “blasphemy against the Holy Spirit”: Matthew 12:22-32, Mark 3:20-30 and Luke 12:10. The Greek word in these verses means “to speak abusively, defame, vilify.” Certain people of Jesus’ day blasphemed the Spirit by attributing the power and works of God to the devil — by saying Jesus cast out demons by an unclean spirit.
Blasphemy against the Spirit of God is not pardonable. The reason is this: We can come to repentance only when the Holy Spirit convicts us that our ways have been wrong and that God’s ways are right. If we reject, by not repenting, the Holy Spirit and the works it does, we are rejecting the only channel through which we could qualify for God’s gift of grace. The unpardonable sin is the one unrepented of.
Falling away after once having the Holy Spirit is also unpardonable (Hebrews 6:4-6). Falling away means turning from God’s way of life after sincerely embracing it, or rejecting Christ’s sacrifice, which makes it possible for humans to receive God’s Spirit after repentance and baptism (Acts 2:38). It is possible, as I Thessalonians 5:19 shows, to quench the Spirit in us.
Many have worried needlessly about this question. No one who has blasphemed the Spirit of God wants to do the works of God. He hates them! But as long as one is truly repentant, wants to live God’s way of life and strives to overcome, he or she has not committed the unpardonable sin.
The Apple Of God's Eye 
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